Discovering genomics proteomics bioinformatics 2nd edition

The use of these approaches to investigate causal mechanisms in specific scenarios e. This volume is therefore an essential read for geneticists, epidemiologists, and all biomedical scientists and public health professionals dedicated to using genetic information to improve human health. In human genetics, causal inference methods leverage large omics data sets and phenotypic information to decipher various cause-and-effect relationships in human health and disease e.

Click to Enlarge. Free shipping offer applies to direct website purchases by individual U. Click here to inquire. Click here for more information. Lung Cancer: Disease Biology and Its Potential for Clinical Translation Lung cancer affects millions of people worldwide and is the leading cause of cancer death in both men and women in the United States.

There are two main types of lung cancer: small-cell and non-small-cell. These cancers grow differently, are treated differently, and lead to different outcomes. Recent advances in the clinic and laboratory are leading to significant enhancements in patient care.

Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine covers the progress that has been made in understanding the molecular pathogenesis of lung cancer and how this information is leading to improved detection and treatment strategies.

The contributors review the genomic, transcriptomic, epigenomic, and proteomic changes associated with lung carcinogenesis, the histologic and metabolic features of different types of lung cancer, and the roles of the immune microenvironment and cancer stem cells in tumor maintenance and metastasis.

The large databases of demographic and clinical information, high-throughput platforms that generate molecular data, advanced computational methods e. In addition, the authors discuss progress on risk prediction, diagnostic strategies e. This volume is therefore a vital reference for all cancer biologists and clinician-scientists devoted to reducing the public health burden of this disease.

Lung cancer affects millions of people worldwide and is the leading cause of cancer death in both men and women in the United States. Special Offers Classic Titles on Sale. Search type two or more letters for suggestions : Or: Advanced Search. Description A new online publication for the molecular life sciences Cold Spring Harbor Perspectives in Biology provides the scientific community with comprehensive, systematic surveys of topics in the molecular life sciences where research is breaking new ground In July , Cold Spring Harbor Laboratory Press launched a new monthly journal, Cold Spring Harbor Perspectives in Biology , that provides comprehensive, systematically structured surveys of research in exciting areas of molecular and cellular biology, genetics, developmental biology, neuroscience, cancer biology, and molecular pathology.

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Remember me on this computer. Enter the email address you signed up with and we'll email you a reset link. Need an account? Click here to sign up. Download Free PDF. Discovering genomics, proteomics and bioinformatics 2.

Share Embed Donate. Report this link Summary: A first textbook for upper-level undergraduates and first-year graduate Upload a Thing! Customize a Thing. Download All Files. Select a Collection. Save to Collection. Tip Designer. Share this thing. Students learn to use databases and how to extract pertinent information. Math Minutes supply brief tutorials that reveal the math behind the biology and illustrate how investigators apply math in solving specific biology problems.

Discovery Questions appear throughout each chapter and ask students to consider what is happening in a particular example or case study, thus engaging students in taking a genomic approach to real-world problems.

Case studies and real-world examples provide a context for understanding the experiments and results. Integrated multimedia and web resources direct students to a full methods index, relevant web links and animations that allow them to research and analyze real genomics data as they work their way through each chapter. Icons in the text alert students to these media tools. New to This Edition.

The text has been thoroughly updated to incorporate the most up-to-date scientific findings and groundbreaking research. Case study chapters have been updated and integrated into the book to tie real-life scenarios into the concepts that follow. Discovery Questions and Math Minutes have been updated and expanded to engage students and encourage critical and quantitative thinking.

Table of Contents 1. Genome Sequence Acquisition and Analysis 3.